First Do No Harm

Weight Loss Secret
How to naturally suppress your appetite.

Weíve touched on this subject recently in our article Name That Hormone and in a discussion about the many, many people who are overweight because they just donít feel full.

Louis CK has a routine about how it takes 40 minutes for the stomach to tell the brain itís full. He says it sure as heck doesnít take the most direct route; probably makes frequent stops talking to the other organs.

Then thereís that leptin resistance. Leptin tells you youíre full. You just donít hear it.

Well, there are two more hormones that tell you your full, and Iím going to show you a way to stimulate them. One important note: do not expect instant results.

We love modern medicine because:

  • you take a pill
  • the problem is gone.

This method is not instant. This is a case of getting a nutrient into your body and allowing it to do its work over a period of time.

The Hormones

There are two hormones that affect appetite we need to discuss. They are CCK (cholecystokinin) and GLP-1 (glucagon-like peptide 1).

CCK is the hormone that stimulates the gallbladder to release bile needed for the digestion of fat and proteins and causes the pancreas to release digestive enzymes. They are created in the epithelial cells of the small intestine and are released in the duodenum, the first section of the the small intestines. [There are four basic types of tissues in animals: connective, muscle, nerve, and epithelial. Epithelial tissues are the outer cells of organs, your arteries and veins, and they also form glands.]

CCK is also a neuropeptide [neuropeptides are small protein-like molecules, or peptides, used by neurons, or never cells, to communicate with each other]. CCK sends a message to the brain that we are satiated. But it takes about 45 minutes. CCK does not go directly to the brain because the blood brain barrier stops it. CCK uses the orexin neurons to get the message out to the appetite, as the orexin neurons are the neurotransmitters involved in sleep/wakefulness, arousal, and appetite.

Though it takes about 45 minutes to tell the brain youíre full, we're about to show you how the feeling can last about 4 to 6 hours, which could stop those midnight snacks.

GLP-1 too is produced by the small intestines and mediates the ďileal brakeĒ function. The ileal break function is exactly as it sounds: GLP-1 slows digestion in the ileum. Allowing digestion to slow keeps blood sugar from spiking and so GLP-1 has a protective role over the pancreatic beta cells that create insulin. And, as you can probably guess, itís also been associated with appetite suppression.

Together, these two hormones act synergistically, which is absolutely positive for people who are insulin and leptin resistant. So how do we do we get them to work?

Pine Nut Oil

In Sibera, the winters are long and hard. Food is scarce. The Russians have survived those long, lean days by munching on Siberian Pine Nuts. They make them feel satiated even though theyíre suffering some pretty acute malnutrition at times.

Studies showed that those taking the placebo had their GLP-1 hormonal levels start to drop just 30 minutes after eating, whereas the subjects on pinolenic acid (pine nut oil) had their levels peak at 3 hours and then slowly come back down at about the same rate they went up. The studies also show that CCK levels (in the experimental group) were raised for more than four hours and that they had 60% more CCK circulating in their blood than the placebo group. [Causey JL. Korean pine nut fatty acids [pinolenic acid] induce satiety-producing hormone release in overweight human volunteers. Paper presented at: American Chemical Society National Meeting & Exposition; March 26-30, 2006; Atlanta, GA.]

Siberian pine nuts are quite expensive. So are the Korean pine nuts. The oil is really expensive.

I had to do a lot of searching, but Iíve found for you a supplement by the people at the Life Extension Foundation thatís pretty darn cheap.

Iíve also got a site for you where I buy my Siberian Pine Nut Oil.

More Benefits of Pine Nut Oil

Now get this: if you are suffering (or you know someone suffering) from ulcers, consuming Pine Nut Oil will soothe those buggers. Extra Virgin Siberian Pin Nut Oil is chock full of antioxidants and phytochemicals that seem to put those H. Pylori bacteria responsible for ulcers in their place.

You see, H. Pylori doesnít seem to attack the epithelial cells of your stomach and small intestines, but rather contribute to a free radical overload. The antioxidants in Siberian Pine Nut Oil not only sooth ulcers, but can act as the perfect preventive.

Another benefit is a Japanese study I found showed that pine nut oil helped lower blood pressure [].

So, for your Extra Virgin Siberian Pine Nut Oil, you will want to go here:

Two things about this site:

  1. we donít have an affiliate account (we donít make a penny from sales)

  2. they also sell 8 oz Sea Buckthorn Oil, the omega-7 oils weíve told you about in the article Chronic Inflammation and in our last newsletter.

Iím going to order a bottle of that Sea Buckthorn Oil and make up some mayonnaise. It might just be the most expensive batch of mayonnaise ever made on planet earth with the ingredients costing over $40.00.

Now here is a link to the Life Extension (our affiliate link) pine nut oil caps: Natural Appetite Control.

Personally, I prefer the oil to the caps, though I have them both. I prefer the oil because there isnít a single salad dressing I make that canít have an ounce of the oil in it. I also now make my Fish Oil Mayo with an ounce of pine nut oil.

And if you are dieting, salads are something you should be snacking on all the time. So imagine making a fresh salad with a raspberry vinaigrette and just enough pine nut oil to make you feel satiated throughout the day.

Not a bad idea, eh?

Further Reading:

The effect of Korean pine nut oil on in vitro CCK release, on appetite sensations and on gut hormones in post-menopausal overweight women


GLP-1 and Appetite Suppression


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