Depression and Nutrition
Eat, drink, and be merry.
We do not catch a bacterial infection
because we don't have enough antibiotics coursing through our blood
stream. We do not get cancer because we do not have enough
chemotherapy in our bodies. We do not get
heart disease because we do not have enough heart medications in our
medicine cabinets. And we do not get clinically depressed because
we're not knocking back enough antidepressants each morning.
In your basic biology class we are taught that
our blood is manufactured, that it begins, in the bone marrow. In Chinese
medicine, we are taught that our blood begins on the end of our fork: we are
what we eat.
"The biggest myth of all is that food has
any connection to behavior," says Steven Pliszka, MD,
professor of psychiatry, University of Texas Health Science
Center at San Antonio (found at WebMD).
Actually, the biggest myth of all is that
physicians know anything about nutrition.
Is there a nutritional connection
to depression? Considering that there is a nutritional connection to nearly
every dis-ease in the books, the odds are on: Yes. While visiting a friend he
opened a book to an underlined statement (telling me, "I bought this book
because of this sentence) that read: "85% of our serotonin is created in the
gut." Serotonin is considered a "brain" chemical. Serotonin, whether created in
the gut or in the brain, begins on the end of your fork.
The Quest for Answers
diagnosed as clinically depressed in 1994. (Six months later they changed that
diagnosis to bipolar.) I was given Zoloft, and my whole world changed. I could
concentrate. I could actually sit down and read without my mind wandering
between paragraphs. I could actually listen to a conversation without my own
thoughts getting in the way. To put it more dramatically, I was not about to
commit the suicide I had planned to commit for months and months. I was just
moments away from the actual act when the whole world opened up and told me,
you'll be fine.
Zoloft saved my life. But the
simple fact is, I was not clinically depressed because I did not
have enough Zoloft in my body. I was clinically depressed because my diet lacked
key nutritional factors.
year or so I discovered that Zoloft was messing with my liver function. I was
then put on Nefazodone. I soon discovered that I was one of the .4% who was
allergic to it and was placed on Wellbutrin, which had the added benefit of
helping me to quit smoking. However, in late 1998, I read an article about an
Celtic Sea Salt. I do not have the original article
today, but I recall that prisoners, especially violent prisoners, were given
Celtic Sea Salt without their knowing it and without the guards being informed
either. Since violent prisoners are split up in these large institutions, there
was in another cell block a control group that was kept on regular table salt.
Guards daily have a lot of paperwork. They have to report "incidents," fill in
queries, and report on events. Within less than a month, reports coming from the
cell block getting the
Celtic Sea Salt showed that incidents were down and behaviors were
significantly improved. Significant simply means that the changes were not due
to "coincidence." The salt had had an effect. (To read our original article on
Celtic Sea Salt, Click
Perhaps the simplest of all studies showing the
connection between nutrition and depression was published in
1995, 32:2, 98-105:
Vitamin supplementation for 1 year improves
by Benton D; Haller
J; Fordy J Department of Psychology, University College Swansea, UK. Here is the
The possibility that the taking
of vitamin supplements may influence mood was explored. One hundred
and twenty-nine young healthy adults took either 10 times the
recommended daily dose of 9 vitamins, or a placebo, under a
double-blind procedure, for a year. Males taking the vitamins
differed from those taking the placebo in that they reported
themselves as feeling more 'agreeable' after 12 months. After 12
months the mood of females taking the vitamin supplement was
significantly improved in that they felt more 'agreeable', more
composed and reported better mental health. These changes in mood
after a year occurred even though the blood status of 9 vitamins
reached a plateau after 3 months: this improvement in mood was
associated in particular with improved riboflavin and pyridoxine
status. In females baseline thiamin status was associated with poor
mood and an improvement in thiamin status after 3 months was
associated with improved mood.
Update (12/08/07): One of our
friends, Dr Robert Rowan sent us a recent newsletter (Second
Opinion) of a new study that shows SSRIs (Selective serotonin
reuptake inhibitors) inhibit the
absorption of calcium into your bones. He says: "Researchers
found that daily use of SSRIs can cause a 4% reduction in bone
mineral density in your hips. The lower spine lost 2.4% of bone
density." Additionally, SSRIs can lower your blood pressure which
can result in falling; a perfect prescription for broken bones.
He goes on
to relate how SSRIs are over prescribed. He notes that Dr David
Golzman, a senior investigator in this study (published in
Arch Intern Med.
2007;167:188-194) discovered that prescriptions for antidepressants
soared by more than 30% between 2000 and 2004, and quotes the
doctor: "And that puts a lot of people at increased risk for
fractures over and above the risk that they already have as a result
of the fact that they're aging and are taking other medication,
which may also predispose to osteoporosis"
Rowen also reminds us that SSRIs
do not work for 70% of those taking them. Dr Thomas Insel, the
directory of the National Institute of Mental Health points out that
only 30% of the healthiest, highly educated, currently employed,
Caucasian women met the criteria for remission, adding: "The gulf
between research and practice has led to the unfortunate current
state where too many research studies have little immediate
relevance to practice, and too little practice is based on research
are not the answer to depression. Perhaps they can help you
initially, but as always, getting to the cause of the problem is
always the best answer.
At one point in my care, my psychiatrist
recommended Lithium. I've seen what people look like on Lithium;
very reminiscent of my early drug days in the sixties. I refused the
drug, but told my psychiatrist I'd get some naturally.
Celtic Sea Salt contains natural Lithium salts.
Celtic Sea Salt is the only salt I'll use
(with the exception of a bit of
Original Himalayan Crystal Salt™ at
times) and I use it on everything. Within
six months a using this salt, I took a battery of tests at the VA
hospital and they told me I was no longer bipolar. I can think of
nothing else I did that would have accomplished this so quickly.
In researching our 3rd Edition of
the Wellness Directory of Minnesota™
with our focus on Cardiovascular Wellness, I discovered that B vitamins
supported heart function; that Congestive Heart Failure, referred to by Dr Bruce
West as "beriberi of the heart," was due to a B vitamin deficiency. Being
thorough, I began reading up on the B vitamin complex and discovered that they
are also brain food.
In the early nineties, there was a
big commercial push for brain nutrients. Every vitamin company had brain drinks
and brain foods and brain stimulants. I recalled that one of the ingredients
common to all these fad mixtures was Choline.
Choline is a B vitamin that is the
precursor of the neurotransmitter acetylcholine and is essential for optimal
memory function. Choline, being water soluble, is absorbed through the blood
barrier and protects and nourishes other chemicals
that support memory. Choline, along with B-12, is necessary for myelin
You've heard that fish is brain food? Well, fish contains a lot of choline.
Choline is also found in eggs, fermented soy, dark greens, liver, yeast, and
Inositol, another part of the
B-complex, is also remarkably effective against depression, panic attacks, and
obsessive-compulsive disorder (OCD) in several studies. The effective dose was
12 grams per day for four weeks. Inositol has no side effects and is as
effective as prescription drugs.
All of the B vitamins are water soluble, meaning
they don't last long in your body and must be replaced (except for B-12 which is
stored in the liver as we will see later).
So I went on to continue my
research into the B vitamins and I found an article by Dr Judith DeCava, PhD
called "Vitamin B Complex in Human Nutrition." She listed symptoms of B vitamin
deficiency and at the top was mild to severe depression. She went on to list:
forgetfulness, vague fears, uneasiness to panic, mood swings, rage, morbid
thoughts, hostility, restlessness, apprehension, constant feeling that something
dreadful is going to happen, suspicions, instability, anxiety, mental confusion,
noise, sensitivity, inability to handle stress, hearing noises, voices, etc.,
loss of ability to concentrate, impaired intellect, loss of memory, nervousness,
loss of ability to concentrate, impaired intellect, loss of memory, nervousness,
weakness, fatigue, lightheadedness or dizziness, digestive problems,
hypochlorhydria (insufficient stomach acid production), constipation or
diarrhea, stomach pains, decreased or increased appetite, craving for sweets,
heart palpitations, chest pains, neuralgia to neuritis, muscular soreness, pain,
tingling or achiness, cold hands and feet, heightened sensitivity to touch
and/or pain, menstrual complaints, soreness of the mouth, dermatitis, acne,
burning or itching eyes, difficulty swallowing, sore throat, hypochondria,
headaches, insomnia or sleep disturbances.
Additionally, I learned that B-12 vitamin
deficiency is common in people over 40 because it (like many of the B vitamins)
relies upon stomach acid to be absorbed. Unlike the other B vitamins, it also
needs to bond with something called "intrinsic factor." Those of Scandinavian,
English, and Irish descent often lack this "intrinsic factor" (produced by the
parietal cells of the stomach). I note the age 40 (though it could happen
earlier) because as we age our digestion slows, we produce less stomach acid and
less intrinsic factor, thus I discovered sublingual forms of B-12 to help my
body absorb it better. There are liquids and little pink pills that you hold
beneath your tongue and facilitate absorption that way.
B-12, though it is water soluble, is stored in
the liver and not washed away like most water soluble vitamins. However, it can
take years before a deficiency in B-12 shows up, though the symptoms can
resemble Alzheimer's disease in extreme cases:
may takes years to develop a B-12 deficiency and the resulting
neurological effects will be noticed before it can be detected by the
usual blood tests. Testing urine levels of methylmelonic [Sic.] acid is
the best way of assessing a B-12 deficiency and will detect it before
the blood levels of B-12 will record outside the normal range. A B-12
deficiency causes slowly progressing and irreversible nerve damage. New
evidence suggests that B-12 can be deficient even though pernicious
anemia is not present. Even in cases where the blood does not indicate
it, B-12 may be dangerously deficient and can contribute to such
problems as mental deterioration, confusion, depression, and other
"Vitamin B Deficiencies" by Karen Railey;
The best form of B-12 is Methylcobalamin.
Methylcobalamin seems to reverse nerve damage and has been reported in medical
literature to help prevent and reverse peripheral nerve damage in conditions
including multiple sclerosis, diabetes, and nerve damage caused by chemotherapy.
Vegetarians are often deficient in B
vitamins as the foods richest in B vitamins are animal products.
There are B vitamin analogues found in yeast and sea weeds, however
there is also a great controversy over whether B vitamin analogues
are the same as B vitamins and let me tell you that, personally,
I've spent the better part of that past two years trying to untie
this little knot to no avail. Someday someone will come forward and
tell us what's up with this, we can only hope.
Folic Acid is part of the B Vitamin
complex and clinical studies abound on how it can relieve depression
better than antidepressants alone, with women in particular
Homocysteine is an intermediary amino acid
associated with a variety of diseases, including heart disease. Elevated levels
of homocysteine has been associated with depression disorders, as well as anger
attacks caused by depression. Your B Vitamin complex contains nutrients that can
lower homocysteine levels.
Few people know that
the brain is 60% cholesterol. Perhaps fewer know that lecithin makes
up about 30% of the dry weight of the brain. Lecithin contains a lot
of choline and contains a vitamin not yet recognized by
nutritionists called vitamin J. Vitamin J is pure brain food and is
needed for good, healthy nerves.
Lecithin also contains
phosphatidyl-serine. It used to be thought that once brain cells die,
they're gone forever and that new brain cells cannot be grown. However,
according to Dr James Balch, MD, more than 60 human studies and over 3000
scientific papers have demonstrated that new brain cells can be grown and even
Alzheimer's symptoms (language deterioration, fatigue, depression, poor
judgment, vision and hearing loss, etc.) can be reversed, and it's the
phosphatidyl-serine that does it.
After further research
into phosphatidyl-serine, it was discovered that all the studies
that got impressive results used a form of phophatidyl-serine that
came from animal fats; or to be even more specific: cow brains. There
are some expensive supplements containing phosphatidyl-serine, but you won't
find any that came from cow brains due to mad cow disease. Studies
on vegetable forms just do not get the same results.
The best B
vitamins are found in food. If you are taking a B vitamin complex, or a daily
multi-vitamin, keep this in mind: most vitamins are crap. You body cannot
survive on synthetic food, how is it supposed to survive on synthetic vitamins?
The best B vitamins made today come from Standard Process Labs, however, they do
not sell to the public; they sell to health care professionals only, doctors and
chiropractors. You can order it by calling Dr Bruce West's vitamin company
called Immune Systems, at 800.231.8063. My second choice would be
NOW Foods, B Complex. They are inexpensive and are not synthetic.
Clinical Rheumatology (July, 2006)
reported on a study in the UK where those suffering from vitamin D
deficiency scored much higher on anxiety and depression tests than
those who had healthy vitamin D levels.
With the spate of studies showing
that Vitamin D can lower your chances of certain cancers by 70%,
everyone should be getting at least 1000 IU of Vitamin D daily.
In the July
07 issue of the New England Journal of Medicine, a report was
published detailing the widespread vitamin D deficiency in our
population ─ as much as one billion people.
The best form of Vitamin D is
Vitamin D-3, the exact same type made in your body by sunlight.
Most nutritional physicians recommend
between 1000 IU and 1500 IU daily, however, on study found that
depression during winter months was significantly reduced among
study subjects who took high daily doses of vitamin D (4,000 IU) for
a period of one year.
Disorder (SAD) is a direct link between depression and lack of
Vitamin D, though the simple lack of sunshine, something that can
brighten up your day, has to be considered. On a dreary day, we just
Vitamin D is very
inexpensive. You get it free from the sun, but when the sun isn't
visible, or you just can't get out into it, it's still pretty cheap.
Check out the prices at the link below:
At one point in my research, I
began experimenting. I'd take my drugs for a week on, then two weeks off. I
realized I was almost there. And then I discovered flax oil, fish oils, and DHA
Johanna Budwig, a biochemist, was reversing cancer and
heart disease with omega-3 fatty acids back in the fifties (in Germany). Little
known is that she was also relieving many mental disorders and childhood
behavioral disorders. Researchers at Harvard Medical school [Omega-3
polyunsaturated fatty acid levels in the diet and in red blood cell membranes of
depressed patients by Edwards R, Peet M, Shay J, Horrobin D University
Department of Psychiatry, University of Sheffield, UK.J Affect Disord 1998 Mar;
3 fatty acids in bipolar disorder: a preliminary double-blind,
placebo-controlled trial by Stoll AL, Severus WE, Freeman MP, Rueter S, Zboyan
HA, Diamond E, Cress KK, Marangell LB. Brigham and Women's Hospital, Department
of Psychiatry, Harvard Medical School, Boston, Mass, USA.
Arch Gen Psychiatry 1999 May; 56(5):407-12;
http://www.biopsychiatry.com/omega3.htm], and in
Bethesda, Maryland [Essential
fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid
among healthy control subjects, and early- and late-onset alcoholics by Hibbeln
JR, Linnoila M, Umhau JC, Rawlings R, George DT, Salem N Jr Laboratory of
Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and
Alcoholism, Bethesda, Maryland, USA. Biol Psychiatry 1998 Aug 15; 44(4):235-42;
have continued on with Budwig's research into omega-3, essential fatty acids.
The conclusion is simple, the lack of essential fatty acids can contribute to
depression, as well as bipolar disorder and including them in your diet can help
to eradicate these same disorders. My only question, when it comes to these
studies, concerns how much better their results might have been had they
administered the omega-3 oils in a water soluble form.
DHA (docosahexaenoic acid) is
found in fish oils. It was discovered that DHA levels were low in alcoholics and
women in their postpartum period. Apparently alcohol helps to deplete DHA
levels. As for women in their postpartum period, because babies need DHA for
proper brain development, in the last stages of pregnancy, the baby "pulls" DHA
from the mother's stores. This is thought to be the cause of postpartum
depression. Studies at Harvard Medical school suggest "...that DHA may be
associated with depression, and the limited data available on supplementation
with DHA or other omega-3 FAs seem to support the hypothesis that DHA may have
psychotropic effects." [Docosahexaenoic
acid and omega-3 fatty acids in depression by Mischoulon D, Fava M Depression
Clinical and Research Program, Department of Psychiatry, Massachusetts General
Hospital and Harvard Medical School, Boston, Massachusetts, USA. Psychiatr Clin
North Am 2000 Dec; 23(4):785-94;
Update: DHA is now found in a product
by Udo, called
Udo's DHA Blend. It comes from algae, meaning vegans and
vegetarians can use it.
when I met Stan Mann and his product Omegasentials™. Though Stan is a vegan (he
avoids any foods that come from animals) his
Omegasentials™ contain fish oils because it is the only way to get your DHA.
This was the final rung of the ladder. Within two weeks of adding the
Omegasentials™ to my daily regimen, I had conquered my depression.
(Omegasentials™ is the most exciting product I have ever found in my research
and if you have yet to read Johanna
Budwig Revisited to learn about its healing potential,
you should do it now. Additionally, the suggested retail price for Omegasentials
is $40.00 per two pound bag.
I've received a few letters from vegans who tell
me that I can get DHA from nuts, flax, etc., but that's because they've read
articles telling them that these foods are a great source for DHA, when in fact,
these foods are a great source for alpha-linolenic acid, which is a biologic
precursor to DHA (and EPA). However, they are created in your body, and if your
body is not in perfect condition, no conversion is possible. The liver can
create DHA if it his healthy and receives the proper nutrition. If your liver
isn't producing it, then you'll have to have a sizable quantity of good bacteria
in your gut. These bacteria take in your alpha-linolenic acid and pass DHA and
EPA. They also pass B Vitamins.
The best probiotics (good bacteria) we've found come from
Just be aware that they will fill your inbox with email after you
make a purchase.
Update: having discovered this paper:
Aust N Z J Psychiatry. 2008 Mar;42(3):192-8; Eur J Clin Nutr,
2007; 61(3): 355-61, we
discovered that the combination of EPA and Probiotics kicks butt in
fighting depression. EPA alone reduced symptoms by 56%, beating the
Prozac group's improvement of 50%. Another study on 124 adults (mean
age 62 years) found that drinking a probiotic-laden milk improved
their mood. Those in the bottom of the "happy" scale were much
higher on the scale after taking the probiotics.
One more thing I learned from my
research is that people who get depressed have a high alkalinity. In
fact, bipolar types can watch the pH of their urine fluctuate from 5
to 8. Testing your urine's pH is a good idea. I lowered my
alkalinity by using Omegasentials™, and by drinking a potassium
broth. Additionally, a shot of apple cider vinegar in the morning
actually helps lower your alkalinity. Here is the potassium broth
|Fill a large pot with 25% potato
peelings, 25% carrot peelings and whole chopped beets (half and half),
25% chopped onions and garlic (more onions than garlic), 25% celery and
dark greens. Add hot peppers to taste (or cayenne pepper). Add enough
distilled/purified water to cover vegetables and simmer at a very low
temperature for a minimum of 2 hours. Strain and drink only the broth,
put the veggies in a compost (I feed my chickens). Make enough for two
days and refrigerate the leftover broth. Do not store for more than two
Having beaten my depression is no guarantee that some event will
not suck me into another fog of depression. For the most part, however, my
chronic/clinical depression is gone and I've beaten my bipolar diagnosis too. One
bad day cannot be equated with clinical depression. We all have our ups and
downs. The main point is, my chronic depression is now a thing of the past.
Should enough stress build up and start to drag me back, my research has
uncovered still more supplements used for depression and anxiety that I have
access to. I don't believe that these supplements are a substitute for good
nutrition, but once in a while we all need help.
St John's Wort has been touted as
a natural anti-depressant. St John's Wort is a drug. Natural or not, it is still
a drug. It should be used only as an emergency stopgap and is no substitute for
Since I did a ton of research over
the past three years, I feel I should pass on to you some of the things I've
found that also fight depression. Some can be used daily, some can be used only
in an emergency. However, do not go this alone. Have a professional work with
you and monitor your progress. And again, there is no substitute for good
Exercise - Another
Research shows that a
moderate exercise program, three times a week is nearly as effective
at relieving depression as antidepressants.
In my struggle to
relieve my depression, I also took up tennis (again...it's been
years). I also began a daily program of Qigong/Tai Chi. This program
has been remarkable.
And getting out on the
tennis courts in the bright sunlight has increased my Vitamin D
stores. The cheapest source of natural Vitamin D is sunlight.
(5-HTP): a direct precursor to serotonin. Proven
to be extraordinarily effective in increasing levels of serotonin in the brain.
However, one out of five people who respond well to 5-HTP relapse after a month.
I've recently found a version of 5-HTP that contains L-tyrosine, a non-essential
amino acid that plays an important role in the production of neurotransmitters
dopamine and norepinephrine. In addition, because L-Tyrosine is necessary
for the synthesis of thyroid hormone and epinephrine (adrenaline), L-Tyrosine
supports healthy glandular function and stress response.
Adapton or Garum
an extract from the brain and stomach of the Great Bluefish. Though
this chemical has a long history of helping many chronic illnesses, it is
primarily used for stress related problems; anxiety, fatigue, and depression. It
is one of the single most effective supplements for these disorders and French
studies seem to prove this out. It is an inexpensive alternative to
anti-anxiety drugs such as Xanax™, Valium™, and Buspar™ or antidepressant drugs
such as Prozac™, Zoloft™, and Paxil™. It is also used in Europe as a replacement
for Ritalin™ in children with ADD.
Garum contains vitamins, minerals,
and Omega-3 essential fatty acids. It's effect is to increase the amount of
calming, endogenous opiates called endorphins. The polypeptides in Garum act as
precursors for endorphins and other neurotransmitters.
A study in Japan showed that Garum
was able to triple the incidence of alpha (brain) waves, something normally
accomplished by narcotics and major anti-psychotic tranquilizers.
Still, for chronic depression, this might be only
a part of the solution.
Colostrum with transfer factor:
comes from the first milking of a cow (found in
the first milkings of every mammal). Normally this is used to boost immune
function, but it also increases beneficial neurotransmitters such as serotonin
and dopamine and prevents their re-uptake. It also seems to improve
concentration and alertness, so much so, that if used late in the day it will
interfere with sleep.
has been found to help in chronic depression, but since it is a hormone, it,
like all hormonal therapies, is a double- edged sword and we feel that the
possible side effects would wipe out any possible positive effects and we cannot
recommend it with a clear conscience. The form I use is called 7-Keto, by NOW
Foods. Here is what they have to say about it: 7-Keto® is a natural occuring
metabolite of DHEA, providing the same benefits of DHEA, without its associated
side effects. Because the body's production of DHEA declines with age, so does
the production of 7-Keto®. Weight gain is a common sign of aging that often
accompanies the decreased production of DHEA and its metabolites.
Supplementation with NOW® 7-Keto® can safely promote thermogenesis, thereby
supporting the maintenance of healthy body weight.
an amino acid. It increases Norepinephrine levels (also associated
with depression) and for those who've relapsed using 5-HTP,
DL-Phenylalanine worked like a charm.
an herb from the Maidenhair tree. Ginkgo, famous for improving memory loss,
contains terpenes that increase circulation to the brain and other parts of the
body (aids in male impotence too), and protect nerve cells. They even seem to
regenerate damaged nerve cells. Ginkgo in a dose of 240 mg per day improves
memory in Alzheimer's patients. If used early enough, it can slow the
progression of Alzheimer's.
Ginkgo has been shown to be a very effective
antidepressant, especially in the elderly. In a study of 40 older patients who
were not responding well to antidepressant medications, one group was given
Ginkgo while the control group got a placebo along with their antidepressant.
They were tested using the Hamilton Depression Scale, and the Ginkgo group
dropped from 14 to 7 after one month and to 4.5 after two months, while the
score for the placebo/antidepressant group went from 14 to 13 over the same time
period. Ginkgo seems to reduce the loss of serotonin receptor sites.
Ginkgo can have some minor side effects (in a
small percentage of people) of mild headaches or mild stomach upset, but these
seem to go away after a short while.
Ginkgo also thins your blood, so
you'll want to discuss all your drugs and supplements with a
nutritionist before adding ginkgo to your regimen.
an analogue of CoQ10. It has many of CoQ10's properties, but does one thing
CoQ10 doesn't: it increases serotonin in the brain.
written up in our
Alternative Cancer Therapies, is the
Longevity Herb from China. In addition to all its wonderful
properties, it also helps to stabilize mood.
MSM: a form of nutritional sulfur that
is also written up at Alternative
Cancer Therapies and is primarily used to support
connective tissue and reverse pain in people with arthritis, also tends to
normalize mood and increase feelings of well-being.
is something we should all be taking daily (I use
it daily). It converts many carcinogens into harmless chemicals, reduces
homocysteine levels, and increases glutathione levels (a powerful antioxidant
and cellular detoxifier). It is also supports our capillary system, has
antiviral properties, and protects the liver. High homocysteine levels are
associated with both depression and heart disease.
the latest craze in the world of alternatives (tons of junk mail
about SAMe in my mail box). However, upon further research, all of
the fabulous results from this supplement were gotten from the
injectable form only. However, we have now found more studies (at
that seem to show that SAMe works better than the placebo in both
depression and pain relief (from chronic inflammation).
(also known as
betaine), and Dimethylglycine DMG, are methyl
donors that help in the production of several brain chemicals and
hence improve mood, energy, wellbeing, alertness, concentration, and
visual clarity. DMG (I use this daily too), has anti-tumor
properties, modulates the immune system, acts as an anti-viral,
anti-bacterial, anti-fungal agent, and increases oxygen utilization,
while decreasing lactic acid formation and making energy production
Vitamin C and
that levels of vitamin C are lower in people with depression. Low
levels of vitamin E are also to major depression.
1999 Dec; 56(2-3):189-94, was a study showing that "There
is now some evidence that major depression is accompanied by
activation of the inflammatory response system (IRS). Other signs of
IRS activation, which have been reported in major depression are
lowered serum zinc (Zn) and serum albumin (Alb) concentrations.
15 to 30 mg daily is the usual dose.
How to Improve Fading Memory and Declining Thinking Skills with Nutrition,
an eBook by Karen Railey.
Institute of Mental Health
The Guide to Depression and Intimacy for Men
Wine and Chocolate